After relaxing for two days, Fu Liang returned to the drug research and development center.
In the past few days, there had been a constant stream of Chinese and foreign media wanting to interview Xinming Pharmaceutical. Many of them were hired by Johnson Johnson to promote themselves in advance.
Fu Liang also avoided the media. It was too annoying to be interviewed every day. The laboratory was still quieter.
Now, the office of the Drug Research and Development Center, especially Fu Liang's office, was filled with information on various new drug projects.
Fu Liang didn't look through all of them himself. Instead, he arranged for the laboratory staff to classify these new drug projects.
Those who did not pass the toxicity test were divided into one category, and those who passed the toxicity test were divided into one category.
The second phase of clinical efficacy did not meet expectations, but the side effects were too great, or it had completely fallen behind the category of similar drugs.
Fu Liang was the boss after all. Why would he need to do such tedious things?
Every day, he would check on the progress of the third stage of the skin color reduction, and then there was nothing important.
As for the work at Xin Ming Pharmaceuticals, he couldn't be bothered. He left it to his father and the other shareholders.
Fu Liang also suggested that his father give more power to the shareholders, not afraid that they would make a mistake.
In any case, according to the company's articles of association, if anyone deliberately harmed the company's interests or unintentionally caused major losses to the company, the major shareholders had the right to forcefully purchase the shares in the hands of other shareholders.
If anyone felt that the money they received was too little, they could forget about splitting it and leave immediately.
At this time, the shareholders of the company were all afraid of being found trouble. They worked especially hard and carefully, which saved Fu Xinming a lot of trouble.
Soon, the information was sorted out and compiled into a new document that appeared on Fu Liang's desk.
Fu Liang understood from his previous research and development of drugs that it was not worth it for him to obtain energy points by developing drugs that could only be used once.
For example, hair removal cream could permanently remove hair after one use, so many people might use it once very quickly.
There was only one energy point that could be provided to Fu Liang.
Only those that could be used repeatedly and were satisfied with each use could provide more energy points.
This would allow him to develop more new drugs faster and create a virtuous cycle.
Although the system was already at Level 3 and could amplify the side effects of drugs by 40 times, it was still far from enough.
Most drugs actually had many side effects, but the probability of many side effects was very low.
Magnifying it by 40 times was not enough.
If he could magnify it by a hundred times or even a thousand times, he could guarantee that he could develop even more divine medicines.
Therefore, this time, Fu Liang's research and development goal for the new drug was to focus on some drugs that had a wide range of applications and could be used repeatedly.
He first looked at some prescriptions that had failed the clinical toxicity test.
Some of them were very harmful to the internal organs, and their metabolism was slow. Even if the dosage was reduced, it would not work.
There were also some that would cause a more obvious allergic reaction. Although many drugs would have allergic reactions, and some were even life-threatening, the probability of allergic reactions to those drugs was not high.
For example, everyone knew that the probability of an allergic reaction was between 0.7% and 10%.
The probability of allergic shock was 0.4 in 10,000, and the mortality rate was close to 0.1 in 10,000.
The extraction technology of penicillin was constantly improving, and the allergic rate was constantly decreasing, but many people were still unwilling to use it.
Similarly, some prescriptions that were highly toxic and knew that eating them would cause serious harm to a young adult did not have the value of continuing to develop.
However, this wasn't impossible for Yu Liang.
Because in the pharmaceutical industry, anything that was said to be highly toxic or deadly without mentioning the dosage was nonsense.
Any poison would only become life-threatening when it reached a certain amount.
A normal person might come into contact with tens of thousands of toxins every day, but most of them were very small. They might be expelled with breathing and had no effect on the human body.
Therefore, if a drug failed the toxicity test, but if it could find strong side effects, then after improvement, the dosage could be reduced to ensure that the toxin could be discharged normally by the human body. It would be a good drug that was welcomed by the market.
However, he still chose to filter the drugs that passed the toxicity test first. This way, he could carry out clinical tests faster and get them on the market earlier.
In the future, when there were no suitable prescriptions to improve, he could come and take a look at these drugs that were abandoned after the first phase of clinical trials.
"This medicine has a serious burden on the kidneys? Why was it only found out in the second phase of clinical trials? Could it be that even 100 milligrams was not enough?”
"This prescription is too harmful to the liver. It won't be easy for the market to recognize it if it labels the side effects that have a great impact on the liver.”
"Hey, this medicine is not bad. The toxicity is not too strong. There are no problems with the first phase of clinical toxicity test.”
Fu Liang searched for a long time and finally saw a medicine that he was slightly interested in.
The first-stage clinical test was not bad. It could be completely digested in about six hours. Unless it was a person with severe liver and kidney incompetence, it should be able to be used.
However, the reason why this drug should not be given up after the second phase of clinical trials was because the effect was too poor.
Only by increasing the dosage could the expected treatment effect be achieved.
However, if the dosage was increased, it would increase the burden on the liver and kidney. Moreover, this medicine had to be taken for a long time because it was a blood pressure medicine.
Most cases of high blood pressure were life-long and required constant medication to control blood pressure.
This blood pressure medicine could indeed control blood pressure after increasing the dosage, but according to calculations, the liver and kidney of a normal person would suffer a serious burden. It was very likely that liver and kidney diseases would occur within a year.
If that was the case, then this medicine was not meant to cure illnesses, but to harm others. Who would take it?
It was not like there were no other options. There were so many safe anti-hyperbaric drugs that had been tested for decades to choose from. Who would take such a drug with such great side effects?
The side effects of this medicine were only on liver and kidney function. Other side effects might not have been discovered yet.
Fu Liang did not need to find someone to do any experiments. He just needed to ask directly.
"System, help me test the side effects of this prescription.”
This drug was mainly developed to treat high blood pressure. Side effects included nausea, cavernous vasodilatation, and so on.
Fu Liang was stunned for a moment, as if he saw some strange effect among the side effects.
The cavernous vasodilatation was similar to the cavernous body of the human body. There was only one part of the cavernous body that had it.
As for the role of cavernous expansion…This made Fu Liang think of a drug that had created a sales legend, Viagra!
This side effect was amazing!
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